Packaging and pharmaceutical form

Each package contains 60 chewable tablets.

Therapeutic effects and pharmacology:

Insufficient intake of vitamin C from food and inadequate body stores can lead to vitamin C deficiency. Additionally, factors such as air pollution, tobacco and cigarette use, fighting certain diseases and infections, and type 2 diabetes increase the body’s need for this vitamin.

Vitamin C is involved in numerous physiological and metabolic processes. Along with its antioxidant effects and protection against free radicals, it plays a key role in the proper functioning of cells involved in the immune system.

Zinc is an essential element involved in many biological processes in the body. Zinc deficiency often results from insufficient dietary intake or poor absorption of this mineral.

Beneficial effects of royal jelly

• Immune System Support: By stimulating the production of immune cells such as lymphocytes and macrophages, it strengthens the immune system and enhances overall immune function and the body’s ability to respond to infections.
• Chronic diarrhea: Due to the antimicrobial activity of royalisin and royalactin, it exhibits anti-diarrheal properties.
• Chronic constipation: The acetylcholine present in royal jelly promotes smooth muscle contraction, possesses antimicrobial properties, and may potentially support regular bowel movements.
• Antioxidant properties: The flavonoids, phenolic compounds, and vitamins in royal jelly neutralize free radicals and reduce oxidative stress.
• Anti-inflammatory effects: Components such as 10-hydroxy-2-decenoic acid (10-HDA) have demonstrated anti-inflammatory properties and help reduce inflammation in conditions like arthritis and skin irritations.
• Neuroprotective Effects: Compounds such as 10-HDA and royalisin have neuroprotective properties and may potentially enhance the survival of nerve cells under various conditions.

Side effects:

Side effects such as stomach irritation, heartburn, nausea, vomiting, headache, hot flashes, and flank pain may rarely occur. High doses of vitamin C can lead to hyperoxaluria (increased excretion of oxalate in the urine), which may increase the risk of oxalate stone formation.

Royal jelly appears to be well tolerated both orally and topically.

The most common side effects:

• Oral: Shortness of breath, eczema, oral allergy syndrome, itching, and hives in individuals with a history of asthma or atopy.
• Topically: contact dermatitis and skin irritation.

Theoretically, royal jelly may increase the risk of low blood pressure when taken with antihypertensive drugs. Using royal jelly alongside warfarin may increase the risk of bleeding.

Drug interactions:

Products containing zinc sulfate should be taken with the following timing intervals: at least 2 hours apart from bisphosphonates and tetracyclines, 3 hours from cephalexin, 1 hour from penicillamine, and 2–4 hours before or 6–8 hours after fluoroquinolones such as ciprofloxacin, levofloxacin, gemifloxacin, moxifloxacin, and ofloxacin. Additionally, due to the presence of vitamin C, this product may interact with estrogen derivatives and aluminum hydroxide.

Theoretically, royal jelly may increase the risk of low blood pressure when taken with antihypertensive drugs. Using royal jelly alongside warfarin may increase the risk of bleeding.

Precautions and warnings:

In cases of kidney failure, continuous use of medications containing aluminum, such as aluminum hydroxide, a history of oxalate stones, hemochromatosis, and G6PD deficiency (favism) should be taken with caution and under a physician’s guidance.

Contraindications:

Avoid using this product if you have oxalate kidney failure.

Royal jelly can cause allergic reactions, including itching, hives, eczema, swelling of the eyelids and face, conjunctival swelling, runny nose, shortness of breath, and worsening of asthma in individuals with asthma. In severe cases, royal jelly can lead to asthma, anaphylaxis, and death. It may also trigger allergic symptoms such as itching, hives, eczema, eyelid and facial swelling, conjunctival swelling, runny nose, shortness of breath, and asthma in people with atopy. If you have asthma, a history of asthma, or atopy, you should avoid using royal jelly.

Pregnancy and breastfeeding:

There is not enough reliable information available about royal jelly. Do not use.

Storage conditions:

Store at a temperature below 25°C, away from light and moisture, and out of reach of children.