Due to the increased nutritional requirements during pregnancy, providing essential vitamins for fetal growth and development is crucial. It has recently been established that supplementation with iodine and folic acid before conception and during the first trimester of pregnancy is essential and significantly reduces the risk of fetal neurological and brain defects.
Folic acid deficiency during pregnancy leads to numerous problems, such as low birth weight and repeated miscarriages.
Pergbion®1 is suitable for supporting maternal and fetal health from preconception through the first trimester of pregnancy. This supplement helps prevent neural tube defects in the fetus and meets the mother’s daily requirements for essential vitamins during this period, ensuring a healthy and high-quality pregnancy.
Meeting the pregnant mother's needs for iodine and folic acid
Meeting the need for essential vitamins and minerals in the first trimester of pregnancy
Maintaining the health of the mother and fetus
Meeting the mother's daily iodine requirement in the form of supplements during pregnancy, according to the American Thyroid Association
Providing the mother's daily need for folic acid during pregnancy to prevent neural tube defects in the fetus
Helping to meet the mother's daily needs for vitamins E, C, and B vitamins during pregnancy
In each capsule:
| Folic acid | 400 micrograms |
| L-methylfolate | 416 micrograms |
| Iodine | 150 micrograms |
| Vitamin B1 | 1.2 mg |
| Vitamin B2 | 1.6 mg |
| Vitamin B5 | 6 mg |
| Vitamin B6 | 1.9 mg |
| Vitamin B12 | 3.5 mg |
| Vitamin E | 13 mg |
| Biotin | 60 micrograms |
| Niacin | 15 mg |
| Vitamin C | 110 mg |
One tablet daily with food for better absorption from the time of decision to become pregnant until the end of the 12th week of pregnancy or as directed by a doctor.
Each box contains 30 oral tablets along with a patient information leaflet.
During pregnancy, the need for nutrients increases to support fetal growth and development. Meeting all of the mother’s nutritional requirements through diet alone is unlikely, and taking supplements is an easy way to fulfill these needs. **Iodine:** The fetus in early pregnancy relies entirely on maternal thyroxine for normal brain development. Adequate iodine intake during pregnancy is essential for maternal thyroxine production and fetal thyroid function. Iodine deficiency during pregnancy can lead to insufficient thyroid hormone production, resulting in irreversible brain damage in the fetus. Therefore, the American Thyroid Association recommends that women take a daily supplement containing 150 micrograms of iodine during pregnancy. Adequate iodine intake before pregnancy is also essential to ensure sufficient thyroid iodine stores. **Folic Acid:** Folic acid (folate) deficiency during pregnancy is associated with multiple complications, including low birth weight, miscarriage, and neural tube defects in the fetus. Taking a folic acid supplement during this period helps prevent these defects, and pre-pregnancy supplementation is also recommended to prevent neural tube abnormalities. **B Vitamins:** Even mild vitamin B12 deficiency in the mother can slow fetal growth and development and may cause permanent effects on the child’s brain. Low maternal B12 levels are also linked to an increased risk of recurrent early miscarriages. B vitamin deficiencies before pregnancy increase the risk of preterm birth, and deficiencies during pregnancy can result in low birth weight infants. **Vitamin C:** This vitamin crosses the placenta, and requirements increase during pregnancy. As an antioxidant, vitamin C protects tissues against free radicals. Low antioxidant levels can lead to oxidative stress, which is a factor in certain pregnancy complications, such as preeclampsia. Studies have shown that vitamin C supplementation can address one of the common causes of infertility, suggesting that pre-pregnancy intake may also enhance fertility. **Vitamin E:** Positive effects of vitamin E as an antioxidant have been reported for reproductive health. Women, especially those of childbearing age, are advised to take this vitamin regularly.
Severe allergic reactions to this product are rare, and symptoms may include skin rashes, redness and inflammation, itching, weakness, and bronchospasm. Other side effects may include diarrhea, nausea, vomiting, metallic taste in the mouth, heartburn, abdominal pain, hives, fatigue, drowsiness, insomnia, headache, runny nose, blurred vision, and hot flashes.
Iodine interacts with lithium, amiodarone, and antithyroid drugs, as these medications can alter iodine levels. Folic acid interacts with methotrexate, phenobarbital, pyrimethamine, and primidone. High doses of vitamin E combined with anticoagulant drugs increase the risk of bleeding. If taking this supplement alongside other products, consult your physician or pharmacist before use.
If you have an autoimmune thyroid disease, consult your doctor before using this product.
Do not use this product if any of the following apply:
* Allergy to any of the ingredients in the product.
* Taking medications for hyperthyroidism, including methimazole, propylthiouracil, potassium iodide, or radioactive iodine (sodium iodide I-131).
It is recommended to use this product from the time you decide to become pregnant until the end of the twelfth week of pregnancy.
Store at a temperature below 25°C, away from light and moisture, and out of reach of children.
